Case Studies | uMotif

Parkinson’s Disease

Multi-nation, fully decentralized Parkinson’s study conducted across 60+ countries
4,200+ participants using personal smartphones, tablets and wearable devices
2.2M+ data points captured, including 1.3M symptom scores and 7,600+ completed PRO questionnaires
Research collaboration with The Cure Parkinson’s Trust, Parkinson’s UK, EPDA, Boston Scientific, Cisco and UCB Pharma

10-week hypoglycemia study with 600 participants across the UK and Europe
Real-time patient-reported hypoglycemia data captured alongside CGM, sleep, quality of life and productivity measures
Most participants achieved >90% questionnaire compliance, with only 1% dropping out after the first week
Led by King’s College London as part of the EU Innovative Medicines Initiative-funded Hypo-RESOLVE project, with published research in BMJ Open and Diabetic Medicine

Fully remote rheumatic fatigue study combining uMotif eCOA/ePRO with dried blood spot sampling
30 days of daily symptom monitoring, including fatigue severity, pain, mood and coping
97.5% average weekly symptom reporting completion and 84% dried blood spot sample completion
Launched in eight weeks, with participants recruited and onboarded in two weeks

Patient-led glioblastoma research initiative designed to advance symptom tracking and data donation
Real-time reporting of sleep quality, exercise, mood, fatigue, quality of life and cognitive assessments
630 patients in the initial study, with a community growing to 1,000+
150,000+ data points captured, with most patients finding symptom tracking useful in managing GBM treatment

Largest remote study investigating sleep disruption and quality of life in adults with rheumatoid arthritis
Hybrid site and virtual model capturing validated questionnaires, symptom data, sleep diaries and sleep tracker data
Study completed six months early, requiring 30% fewer participants than expected
177 patients submitted complete data, generating 100,000+ data points and supporting published research in BMJ Open

Nationwide UK smartphone study exploring the relationship between chronic pain and local weather
Daily patient-reported pain, fatigue, sleep, mood, activity, GPS and weather data captured for six months or longer
13,000+ participants recruited, including 6,000+ in the first week
5M+ data points captured, with results published in Nature and significant links found between pain, humidity, pressure and wind speed

12-week cardiac rehab pilot combining uMotif eCOA/ePRO, smartphones and wearable activity monitors
Daily tracking of cardiac rehab symptoms, exercise effort, heart rate, mood, stress and sleep quality
40% improvement in aerobic capacity and 8% lower systolic blood pressure versus traditional care
150,000 symptom scores recorded, with digital reporting reducing manual admin for Papworth Hospital clinicians